Zoloft is an antidepressant medication developed by Pfizer. It is majorly used to treat clinical depression in adults and children. Over a period of time, the medication’s use got evolved further and it was indicated for the treatment of social anxiety disorder and panic disorder. Zoloft retained the number two spot in terms of prescription. This indeed demonstrates its healing potential. Sertraline is the primary ingredient contained in this drug, and which is responsible for restoring balance in the brain chemicals. There is sufficient evidence to prove the effectiveness of the pill in treating vascular headaches and premature ejaculation. On a comparative note, Zoloft is considered to be highly powerful in treating certain subtypes of depression which is not possible with other antidepressant medications.

Zoloft’s mechanism of action

Zoloft is very efficient in blocking the neuronal uptake of serotonin in central nervous system, thereby ensuring balance in the brain chemicals. The peak effects of the medication are observed anywhere between 4.5 hours to 8.4 hours. The elimination half-life of the pill is 26 hours. The medication is extensively metabolized in the liver. The active ingredient Sertraline is highly bound to serum proteins.